JCDD, Vol. 10, Pages 433: Mapping of Neuro-Cardiac Electrophysiology: Interlinking Epilepsy and Arrhythmia

JCDD, Vol. 10, Pages 433: Mapping of Neuro-Cardiac Electrophysiology: Interlinking Epilepsy and Arrhythmia

Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd10100433

Authors: Sidhartha G. Senapati Aditi K. Bhanushali Simmy Lahori Mridula Sree Naagendran Shreya Sriram Arghyadeep Ganguly Mounika Pusa Devanshi N. Damani Kanchan Kulkarni Shivaram P. Arunachalam

The interplay between neurology and cardiology has gained significant attention in recent years, particularly regarding the shared pathophysiological mechanisms and clinical comorbidities observed in epilepsy and arrhythmias. Neuro-cardiac electrophysiology mapping involves the comprehensive assessment of both neural and cardiac electrical activity, aiming to unravel the intricate connections and potential cross-talk between the brain and the heart. The emergence of artificial intelligence (AI) has revolutionized the field by enabling the analysis of large-scale data sets, complex signal processing, and predictive modeling. AI algorithms have been applied to neuroimaging, electroencephalography (EEG), electrocardiography (ECG), and other diagnostic modalities to identify subtle patterns, classify disease subtypes, predict outcomes, and guide personalized treatment strategies. In this review, we highlight the potential clinical implications of neuro-cardiac mapping and AI in the management of epilepsy and arrhythmias. We address the challenges and limitations associated with these approaches, including data quality, interpretability, and ethical considerations. Further research and collaboration between neurologists, cardiologists, and AI experts are needed to fully unlock the potential of this interdisciplinary field.