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Molbank, Vol. 2024, Article M1881: rel-(2R,3S)-2-((Diphenylmethylene)amino)-5-oxo-5-phenyl-3-(thiophen-2-yl)pentanenitrile
Molbank doi: 10.3390/M1881
Authors: Donka N. Tasheva Vesela M. Mihaylova
The reaction of 2-((diphenylmethylene)amino)acetonitrile with (E)-1-phenyl-3-(thiophen-2-yl)prop-2-en-1-one was performed by using 33% NaOH in CH3CN for 30 min at 0 °C. The main product—rel-(2R,3S)-2-((diphenylmethylene)amino)-5-oxo-5-phenyl-3-(thiophen-2-yl)pentanenitrile—was isolated and characterized by IR, 1H NMR, 13C NMR, 1H-1H COSY, and high-resolution mass spectrometry (HRMS).
