More than 100,000 people in the US died of drug overdoses in 2023

Sobering figure obscures the fact that the number of overdose deaths in the US declined for the first time since 2018

An estimated 107,543 people died of drug overdoses in the US in 2023, a shocking figure that obscures a glimmer of hope – this is the first annual decline in drug overdose deaths since 2018.

The grim toll represents Americans’ struggle with powerful synthetic drugs, in particular the synthetic opioid fentanyl, known to be up to 100 times stronger than morphine. More than 1 million people have died of a drug overdose since 2001, according to the Centers for Disease Control and Prevention.