Toxics, Vol. 11, Pages 380: Advances in the Utilization of Zebrafish for Assessing and Understanding the Mechanisms of Nano-/Microparticles Toxicity in Water

Toxics, Vol. 11, Pages 380: Advances in the Utilization of Zebrafish for Assessing and Understanding the Mechanisms of Nano-/Microparticles Toxicity in Water

Toxics doi: 10.3390/toxics11040380

Authors: Pengyu Lei Wenxia Zhang Jiahui Ma Yuping Xia Haiyang Yu Jiao Du Yimeng Fang Lei Wang Kun Zhang Libo Jin Da Sun Junbo Zhong

A large amount of nano-/microparticles (MNPs) are released into water, not only causing severe water pollution, but also negatively affecting organisms. Therefore, it is crucial to evaluate MNP toxicity and mechanisms in water. There is a significant degree of similarity between the genes, the central nervous system, the liver, the kidney, and the intestines of zebrafish and the human body. It has been shown that zebrafish are exceptionally suitable for evaluating the toxicity and action mechanisms of MNPs in water on reproduction, the central nervous system, and metabolism. Providing ideas and methods for studying MNP toxicity, this article discusses the toxicity and mechanisms of MNPs from zebrafish.